Soft tissue fillers like Juvederm®,Voluma, Volbella, Vollure, RestylaneLyft, Belotero and Radiesse® are commonly utilized agents to restore generalized facial volume loss that occurs with age and thus regain a more youthful appearance. Signs of volume loss include hollowness beneath the eyes, heavy lines between the nose and upper lip (nasolabial folds), loss of fullness of cheeks, thinning of lips, vertical ‘smokers’ lines on upper and lower lips (even in people who have never smoked!), loss of projection of chin, downward turning of the corners of the mouth. A somewhat under-recognized truth is that fullness, as opposed to “tightness” is perhaps the most important hallmark of youth. Plastic surgery removes excess tissue or repositions structures that have fallen while fillers restore volume lost with aging process. The selection of the type of filler to be used and the quantity is dependent on the area desired for re-volumization and the level of correction needed by the treating provider. Most soft tissue fillers will last 9-12 months.